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Old 04-06-2004, 09:22 AM
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Diethylene glycol monobutyl ether
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Products that contain this ingredient

Brand Category Form Percent

Wagner Premium Brake Fluid Auto products liquid 4-12
Wagner Premium Brake Fluid-11/26/2002 Auto products liquid 10-20
Prestone Heavy Duty Brake Fluid Auto products liquid
Gunk Motor Flush Auto products liquid 4-5
Zep Antibacterial Disinfectant and Cleaner with Lemon Home inside pump spray 5-15
Lysol Disinfectant Basin Tub and Tile Cleaner All Scents (Trigger Spray) Home inside pump spray 6
Lysol Basin Tub & Tile Cleaner Foaming Disinfectant Cleaner Home inside aerosol 5.6
Easy-Off Fume Free Max Oven Cleaner Home inside aerosol 7-11
Mr. Muscle Oven and Grill Cleaner Home inside aerosol 10-15
Zep Stain Resistant Floor Sealer-03/21/2002 Home inside liquid 1-10
Mr. Clean Ultra All Purpose Cleaner Home inside liquid
Dawn Power Dissolver Home inside viscous liquid
Mr. Muscle Oven and Grill Cleaner-Aerosol Home inside aerosol 10-30
Easy Off Heavy Duty Oven Cleaner-Original Home inside aerosol 1-5
Lysol Brand Disinfectant All Purpose Cleaner All Scents (Concentrate) Home inside liquid 0-5
Lysol Disinfectant Direct MultiPurpose Cleaner Home inside pump spray 5.99
Zep Antibacterial Disinfectant and Cleaner with Lemon-04/15/2002 Home inside pump spray 1-10
Tough Act Disinfectant Bathroom Cleaner (liq) Home inside liquid <10
Tilex Spray Soap Scum Remover-09/01/1997 Home inside pump spray <8
Zep Stain Resistant Floor Sealer Home inside liquid <5
Lysol Basin Tub & Tile Cleaner Home inside pump spray 6.0
Easy-Off Fume Free Max Oven Cleaner-05/18/2000 Home inside aerosol 5
Zep Pine Scented Disinfectant and Cleaner-02/25/2002 Home inside pump spray 1-10
Dow Disinfectant Bathroom Cleaner IV with Scrubbing Bubbles Home inside pump spray <10
Zep Pine Scented Disinfectant and Cleaner Home inside pump dispenser 5-15
Lysol Brand Disinfectant All Purpose Cleaner Fresh Scent (Concentrate) Home inside liquid 0-5
Lysol Antibacterial Kitchen Cleaner Home inside pump spray 5.99
Tough Act Disinfectant Bathroom Cleaner (aero) Home inside aerosol <10
Mr. Muscle Oven and Grill Cleaner-03/07/2002 Home inside aerosol 10-30
Spic and Span Heavy Duty Degreaser Home inside liquid
Toilet Duck Thick Liquid Toilet Bowl Cleaner Home inside liquid 1-5
Easy-Off Heavy Duty Oven Cleaner Home inside aerosol 5
Zep Floor Finish for High Traffic Floors-02/25/2002 Home inside liquid 0-10
Dow Disinfectant Bathroom Cleaner III with Scrubbing Bubbles Home inside aerosol <10
Duron Weathershield Exterior Acrylic Semi-Gloss, One Coat White Home maintenance liquid 1.1
Behr Premium Plus Hi-gloss Exterior Acrylic Enamel, No 8050 Ultra Pure Wh Home maintenance liquid 3.24
Glidden Ultra-Hide Aquacrylic Gripper All-Purpose Stain Killer Primer, Whit Home maintenance liquid 1-5
Duron Weathershield Exterior Acrylic Semi-Gloss, White Base Home maintenance liquid 1.1
Minwax Lustre Stain Accent Color & Finish, Ranch Walnut-4240 Home maintenance liquid 2
Duron Signature Select Interior Acrylic Semi-Gloss, Midtone Base Home maintenance liquid <0.6
Behr Premium Plus Interior Hi-Gloss 8600 Accent Base Home maintenance liquid 4
Duron Weathershield Exterior Acrylic Semi-Gloss, Neutral Base Home maintenance liquid 1.1
Duron Weathershield Exterior Acrylic Semi-Gloss, Accent Base Home maintenance liquid 1.1
Minwax Lustre Stain Accent Color & Finish, Mahogany-4220 Home maintenance liquid 2
Duron Signature Select Interior Acrylic Semi-Gloss, White Base Home maintenance liquid <0.6
Thoroshield Home maintenance liquid 2
Americas Finest Premium Interior Acrylic Latex Satin Enamel, Accent Base Home maintenance liquid
Behr Premium Plus Interior Hi-Gloss 8300 Deep Base Home maintenance liquid 3
Duron Weathershield Exterior Acrylic Semi-Gloss, Deep Base Home maintenance liquid 1.1
Minwax Lustre Stain Accent Color & Finish, Briarwood-4250 Home maintenance liquid 2
Fletco Elite Diamond Stain Home maintenance liquid 1
Minwax Lustre Stain Accent Color & Finish, White Oak-4200 Home maintenance liquid 2
Aqua Mix Coating and Sealer Stripper Home maintenance liquid
Duron Weathershield Exterior Acrylic Semi-Gloss, High Hiding White Home maintenance liquid 1.1
Aqua Mix Sealer and Adhesive Remover 1 Home maintenance liquid
Duron Weathershield Exterior Acrylic Semi-Gloss, Midtone Base Home maintenance liquid 1.1
Duron Weathershield Exterior Acrylic Semi-Gloss, Amber White Home maintenance liquid 1.1
Minwax Lustre Stain Accent Color & Finish, Redwood-4230 Home maintenance liquid 2
Duron Signature Select Interior Acrylic Semi-Gloss, One Coat White Home maintenance liquid <0.6
Behr Crystal Clear Gloss Home maintenance liquid 0.14
Behr Premium Plus Interior Hi-Gloss 8500 Pastel Base Home maintenance liquid 3
Duron Weathershield Exterior Acrylic Semi-Gloss, Wheat Home maintenance liquid 1.1
Behr Premium Plus High Gloss Enamel No. 8050 Ultra Pure White Home maintenance liquid 3.24
Minwax Lustre Stain Accent Color & Finish, Golden Pine-4210 Home maintenance liquid
Behr Premium Plus High Gloss Enamel No. 8050 Ultra Pure White-03/11/2002 Home maintenance liquid 4

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DIETHYLENE GLYCOL MONO-N-BUTYL ETHER
CASRN: 112-34-5


Human Health Effects:



Human Toxicity Excerpts:

SYMPTOMATOLOGY: B. DIETHYLENE GLYCOL ... 1. CENTRAL NERVOUS DEPRESSION ... 2. NO HYPOCALCEMIC TETANY OR METABOLIC ACIDOSIS ... 3. NAUSEA, VOMITING, & SOMETIMES DIARRHEA. 4. ... HEADACHE. LATER ABDOMINAL & LUMBAR PAIN & COSTOVERTEBRAL ANGLE TENDERNESS. 5. TRANSIENT POLYURIA & THEN OLIGURIA, PROGRESSING TO ANURIA. 6. ACUTE RENAL FAILURE ... 7. ... PATHOLOGICAL LESIONS MAY APPEAR IN BRAIN, LUNG, LIVER, MENINGES & HEART. 8. OBSERVATIONS IN ANIMALS SUGGEST REMOTE POSSIBILITY OF PULMONARY EDEMA, INTRAVASCULAR HEMOLYSIS & BONE MARROW DEPRESSION, @ LEAST WITH SOME ETHER DERIV OF ETHYLENE & DIETHYLENE GLYCOLS. /DIETHYLENE GLYCOL & DERIV/
[Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984.,p. III-176]**PEER REVIEWED**


SLIGHTLY MORE TOXIC THAN ETHYL DERIVATIVE (= CARBITOL) BUT OTHERWISE PRESUMABLY LIKE IT. BOTH RESEMBLE ETHYLENE GLYCOL IN TOXICITY & TOXIC ACTIONS.
[Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984.,p. II-181]**PEER REVIEWED**


RESULTS OF LIMITED REPEATED DOSE ORAL WORK REPORTED SUGGESTS THAT MATERIAL MAY BE RATHER TOXIC WHEN INHALED OR ABSORBED THROUGH SKIN IN REPEATED SMALL DOSES.
[Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982. 3964]**PEER REVIEWED**


THE ETHERS OF DIETHYLENE GLYCOL ARE LOWER IN TOXICITY THAN THE ETHERS OF ETHYLENE GLYCOL, BUT THEY HAVE MANY SIMILAR CHARACTERISTICS. /DIETHYLENE GLYCOL ETHERS/
[International Labour Office. Encyclopedia of Occupational Health and Safety. Vols. I&II. Geneva, Switzerland: International Labour Office, 1983. 975]**PEER REVIEWED**


... When humans were patch tested with undiluted material, a limited number of the volunteers developed reddening of the skin.
[Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982. 3965]**PEER REVIEWED**



Human Toxicity Values:

It has been estimated that the single oral dose /of diethylene glycols/ lethal for humans is approximately 1 ml/kg. /Diethylene glycols/
[Amdur, M.O., J. Doull, C.D. Klaasen (eds). Casarett and Doull's Toxicology. 4th ed. New York, NY: Pergamon Press, 1991. 704]**PEER REVIEWED**



Skin, Eye and Respiratory Irritations:

MODERATELY IRRITATING & INJURIOUS TO EYES, NOT APPRECIABLY IRRITATING TO SKIN ... .
[Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982. 3913]**PEER REVIEWED**



Probable Routes of Human Exposure:

The most probable route of human exposure to diethylene glycol mono-n-butyl ether is by inhalation, dermal contact and ingestion. NIOSH (NOES Survey as of 3/28/89) has statistically estimated that 444,917 workers (136,515 of these are female) are potentially exposed to diethylene glycol mono-n-butyl ether in the USA(1). A study initiated in 1983, which surveyed the workplace atmospheres of 336 businesses in Belgium, showed that diethylene glycol mono-n-butyl ether was present in 7 of 67 samples from sites where various materials such as varnishes, sterilization agents and cleaners are employed(3). Non-occupational exposures may occur among populations with contaminated drinking water supplies(2) and from inhalation of household products(4).
[(1) NIOSH; National Occupational Exposure Survey (NOES) (1989) (2) Lucas SV; GC/MS Anal of Org in Drinking Water Concentrates and Advanced Treatment Concentrates Vol 1 USEPA-600/1-84-020A (NTIS PB85-128239) p. 397 (1984) (3) Veulemans H et al; Am Indust Hyg Assoc J 48: 671-7 (1987) (4) USEPA; Compilation and Speciation of National Emissions Factors for Consumer/Commercial Solvent Use. Information Compiled to Support Urban Air Toxics Assessment Studies. US EPA, Off Air Radiat, Off Air Qual Plan Stand, Research Triangle Park, NC. USEPA/450/2-89/008, PB89-207203 (1989)]**PEER REVIEWED**

-------------------------------------------------------------------------------No doubt it is a dangerous chemical when abused. To use it properly you would need good ventilation, a vapor mask, and chemical resistant gloves. Seems to me any chemical you use for 30+ years, no matter how small of a toxicity level it reportedly has, will end up causing you problems. Especially if you don't follow the directions right on the label. All things in moderation huh?
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