The Army sponsored the world's largest HIV vaccine trial, recently conducted in Thailand that tested a "prime-boost" vaccine strategy composed of two investigational vaccines, ALVAC and AIDSVAX B/E.
This successful international collaboration involved officials from Thailand, the U.S. National Institute of Allergy and Infectious Diseases, the U.S National Institute of Health, the Department of Defense, private and commercial companies and more than 16,000 Thai volunteers who were HIV-negative.
Both men and women between the ages of 18 to 30 participated in the study. Half of the participants received the prime-boost vaccine regimen and half received a placebo. Volunteers received vaccinations over the course of 6 months and were followed for an additional 3 years. Volunteers also received HIV tests every 6 months for 3 years following the vaccination.fficeffice" />>>