USS Guam, the second large cruiser of the 27,500-ton Alaska class, was built at Camden, New Jersey, and was commissioned in September 1944. After shakedown training in the Caribbean she left for the Pacific in January 1945 and joined the fast carrier task forces at Ulithi a few months later. Guam provided anti-aircraft protection during a carrier raid on the Japanese home islands in March 1945 and then fired a shore bombardment mission and supported carrier operations during the Okinawa campaign. In July and August 1945 she joined her sister Alaska and four light cruisers in an anti-shipping raid into Japanese home waters.

After the Japanese surrender Guam showed the flag off the major ports in the Yellow Sea and at Jinsen (Inchon), Korea, before returning to the United States in December 1945. She was decommissioned at Bayonne, New Jersey in February 1947 and remained there until sold for scrapping in May 1961.