USS Sinclair, a 1109-ton Clemson class destroyer built at Squantum, Massachusetts, was commissioned in October 1919. She was designated DD-275 in July 1920. In March 1920, following brief operations in the Western Atlantic and Caribbean areas, she was transferred to the Pacific and was based there for the rest of her career. The destroyer made a cruise to Alaska in mid-1920, participated in training and tactical exercises off the West Coast, and was out of commission at San Diego, California, during most of 1922 and 1923. After returning to active service, early in 1924 she passed through the Panama Canal for a few months of Fleet exercises in the Caribbean. In mid-1925 Sinclair accompanied the Battle Fleet on its trans-Pacific voyage to Australia, New Zealand and Samoa. The next four years were spent conducting routine training and readiness operations in the Eastern Pacific, punctuated by Caribbean maneuvers in 1927 and service in Hawaiian waters in 1928. Sinclair was placed out of commission in June 1929 at San Diego. In November 1930 she was briefly renamed Light Target Number 3 and redesignated IX-37, but reverted to her original name and hull number several months later, after the cancellation of her conversion to a target ship. USS Sinclair was sold for scrapping in August 1935.