USS Biloxi, a 10,000-ton Cleveland class light cruiser built at Newport News, Virginia, was commissioned at the end of August 1943. Late in the year, after a training cruise along the U.S. East Coast and in the Caribbean area and post-shakedown overhaul, the new cruiser steamed to the Pacific to join the war against Japan. In 1944 she was primarily assigned to screen the carrier striking forces during their frequent attacks on Japanese-held islands and in the battles of the Philippine Sea in June 1944 and Leyte Gulf in October. She also used her guns to bombard enemy positions during the assaults on the Marshall Islands in January-February 1944, Northern New Guinea in April.

Biloxi's work with the carriers continued during the first months of 1945, as the war moved up to Japan. In addition she bombarded Iwo Jima when that island was invaded in February. During late March and the first weeks of April her guns actively supported the landings and ground operations on Okinawa. While taking part in pre-invasion bombardment there on 27 March Biloxi was hit by a Japanese suicide attack plane, but damage was relatively light and she remained in action. A West Coast shipyard overhaul kept her away from the combat zone from late April until mid-August 1945, and the end of the war came just as she arrived back in the Western Pacific. From then until early November Biloxi supported the occupation of Japan. Returning to the U.S. late in 1945, she soon began inactivation preparations, decommissioning at Bremerton, Washington, in October 1946. She was part of the Pacific Reserve Fleet for the next decade and a half. USS Biloxi was stricken from the Naval Vessel Register in September 1961 and sold for scrapping in March 1962.